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Tetracaine hydrochloride

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Catalog No. T1198Cas No. 136-47-0
Alias Tetracaine HCl, Amethocalne HCl, Amethocaine hydrochloride

Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been used for surface and spinal anesthesia.

Tetracaine hydrochloride

Tetracaine hydrochloride

🥰Excellent
Purity: 99.86%
Catalog No. T1198Alias Tetracaine HCl, Amethocalne HCl, Amethocaine hydrochlorideCas No. 136-47-0
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been used for surface and spinal anesthesia.
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500 mg47 €In Stock
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Purity:99.86%
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Product Introduction

Bioactivity
Description
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been used for surface and spinal anesthesia.
AliasTetracaine HCl, Amethocalne HCl, Amethocaine hydrochloride
Chemical Properties
Molecular Weight300.824
FormulaC15H25ClN2O2
Cas No.136-47-0
SmilesCl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
Relative Density.1.1279 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 28 mg/mL (93.1 mM)
H2O: 55 mg/mL (182.8 mM)
DMSO: 40 mg/mL (132.97 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO/H2O
1mg5mg10mg50mg
1 mM3.3242 mL16.6210 mL33.2420 mL166.2101 mL
5 mM0.6648 mL3.3242 mL6.6484 mL33.2420 mL
10 mM0.3324 mL1.6621 mL3.3242 mL16.6210 mL
20 mM0.1662 mL0.8311 mL1.6621 mL8.3105 mL
50 mM0.0665 mL0.3324 mL0.6648 mL3.3242 mL
DMSO/H2O
1mg5mg10mg50mg
100 mM0.0332 mL0.1662 mL0.3324 mL1.6621 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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